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Univariate and multivariate odds ratio of asthma severity (GINA Step III and IV Combined) According to asthma risk factors and smoking variables
Variables
Univariate Odds Ratio (95% CI)
P value
Multivariate Odds Ratio (95% CI)
Gender
Female
1.00
Male
1.14 (0.58-2.23)
P = 0.71
Age
1.07 (1.01-1.31)
P = 0.027
Family Hx of Atopy
0.76 (0.37-1.58)
P = 0.46
Model 1 (n = 61)
1.07 (0.31-3.66)
P = 0.92
1.19 (0.32-4.50)
P = 0.79
Passive Smoking
Model 2 (n = 152)
P = 0.043
Current or Former Smoker
2.10 (1.03-4.31)
1.93 (0.93-4.01)
P = 0.08
Model 3 (n = 125)
Packs per Year
Never Smoker 0
1-10 packs 1
1.31 (0.43-4.03)
P = 0.63
1.47 (0.46-4.68)
P = 0.52
11-20 packs 2
3.51 (1.39-8.83)
P = 0.008
2.85 (1.09-7.46)
P = 0.032
>20 packs 3
7.67 (2.09-28.07)
P = 0.002
5.59 (1.44-21.67)
P = 0.013
Model 4 (n = 142)
Smoking Status
Former Smoker 1
1.28 (0.39-4.22)
P = 0.69
1.26 (0.37-4.24)
Current Smoker 2
3.07 (1.43-6.57)
P = 0.004
2.78 (1.28-6.08)
P = 0.009
Model 1: Reference group are nonsmokers not exposed to passive smoking. Past and current smokers excluded.
Model 2: Reference group are nonsmokers. No exclusions.
Model 3: Past smokers and those who quit during follow up excluded.
Model 4: Those who quit smoking during follow up excluded
Results from the univariate and multivariate analyses of measures of asthma severity are presented in Table 2.
by Polosa, Riccardo; Russo, Cristina; Caponnetto, Pasquale; Bertino, Gaetano; Sarvà, Maria; Antic, Tjana; Mancuso, Stefania; Al-Delaimy, Wael KJournal: Respiratory Research Vol. 12 Issue 1DOI: 10.1186/1465-9921-12-16Published: 2011-12-01Institution(s): Università di Catania, U.O. neuroriabilitazione intensiva, University of California
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