a Survival of patients with stage IVa (thoracic upper third + cervical lymph node) (A), stage IVb (non-regional lymph node metastases) (B) and stage IVb (systemic organ metastases) (C) disease. A vs. B, p = 0.08, A vs. C, p = 0.0002, B vs. C, p = 0.0066. b Survival of patients with stage Iva and IVb (non-regional lymph node metastases) (A + B) compared to those with stage IVb (organ metastases) (C). p < 0.001.
Patient survival was also assessed stratified according to the
pretreatment clinical staging (Fig. 4 a,b).
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