Case 5: at 3D level, Pagetoid spread manifests as a continuous intramural growth along the duct (arrows). The arrowhead shows serpiginous vessels. Inset: the corresponding histological section as seen with HM
LN spread intramurally along larger ducts from acini, presenting
the features of “Pagetoid spread” in two cases (cases 3 and 5)
(Fig. 5 ).
Duct walls appeared as thickened, bluish structures (Fig. 5
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