CHM showing no immunoreactivity for p57KIP2 in either cytotrophoblasts and syncytiotrophoblast; note the positive nuclear staining of decidual cells that served as a positive internal control (Immunoperoxidase staining ×400)
All 22 cases that had been morphologically diagnosed as “CHM”,
exhibited a striking lack of p57KIP2 expression in both villous
cytotrophoblasts and stromal cells, as expected (Fig. 3).
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