Simulation results showing the accuracy and precision of rBROOK1 (a, b, c), rCHAK (d, e, f) and rBROOK2 (g, h, i), for N of 20 (a, d, g), 50 (b, e, h) and 100 (c, f, i) individuals performed in the 34 simulated populations described in Table . Simulated populations are placed in the same order in these graphs as in Table
The accuracy of the estimators was variable (Fig. 4 ).
BROOK1 consistently underestimated null
allele frequencies (Fig. 4 a–c).
In contrast, estimations with rCHAK were
accurate, but their confidence intervals were very wide (Fig.
The results obtained with rBROOK2 are far
better since null allele frequencies are accurately estimated
regardless of the parameters values (Fig. 4 g–i). .
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