Stability of reduced N-acetylcysteine (NAC) after dilution of the Parvolex to 120 mg ml−1 with saline and storage in a syringe at room temperature for the time shown. Each bar shows the percent of the NAC in the reduced form and is the mean (SD) of ten samples.
The pharmacokinetics of NACR and NACT were modelled separately, and
since the drug input was virtually entirely in the reduced form
(Fig. 1 ), the same input data were used for each analysis.
The change of NAC in the reduced form measured over time are shown
in Fig. 1 .
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