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LD50 and LC50 values for PFOS and PFOA (from ; BfR  enhanced)
251 mg/kg BW
430 to 680 mg/kg BW
Dean and Jessup 
5.2 mg/L, inhalative
0.98 mg/L, inhalation
4, 300 mg/kg APFO, dermal
7, 000 mg/kg
7, 500 mg/kg, dermal
2, 000 mg/kg, dermal
Glaza et al. 
27 to 233 mg/L
10 to 178 mg/L
181 to 732 mg/L
337 to 672 mg/L
Four fresh water species (water flea, water snail, shrimp, planarian)
Japanese water flea
Ji et al. 
n.r., Not reported.
Table 21 summarizes the various LD50 and LC50
Stahl, Thorsten; Mattern, Daniela; Brunn, HubertusJournal: Environmental Sciences Europe
Issue 1DOI: 10.1186/2190-4715-23-38Published: 2011-12-01Institution(s):
Hessian State Laboratory
Perfluorinated compounds [PFCs] have found a wide use in industrial products and processes and in a vast array of consumer products. PFCs are molecules made up of carbon chains to which fluorine atoms are bound. Due to the strength of the carbon/fluorine bond, the molecules are chemically very stable and are highly resistant to biological degradation; therefore, they belong to a class of compounds that tend to persist in the environment. These compounds can bioaccumulate and also undergo biomagnification. Within the class of PFC chemicals, perfluorooctanoic acid and perfluorosulphonic acid are generally considered reference substances. Meanwhile, PFCs can be detected almost ubiquitously, e.g., in water, plants, different kinds of foodstuffs, in animals such as fish, birds, in mammals, as well as in human breast milk and blood. PFCs are proposed as a new class of 'persistent organic pollutants'. Numerous publications allude to the negative effects of PFCs on human health. The following review describes both external and internal exposures to PFCs, the toxicokinetics (uptake, distribution, metabolism, excretion), and the toxicodynamics (acute toxicity, subacute and subchronic toxicities, chronic toxicity including carcinogenesis, genotoxicity and epigenetic effects, reproductive and developmental toxicities, neurotoxicity, effects on the endocrine system, immunotoxicity and potential modes of action, combinational effects, and epidemiological studies on perfluorinated compounds).
This table is from the article titled "Toxicology of perfluorinated compounds"
(from Environmental Sciences Europe), which is copyrighted by Stahl et al; licensee Springer. For more information on the
copyright for this table, please refer to the full table caption and to the
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