IR spectra of a finasteride:β-cyclodextrin physical mixtures and b finasteride:β-cyclodextrin inclusion complexes
In the physical mixtures, the spectra are the superposition of
those of the pure products with attenuation of the finasteride
peaks (Fig. 6a).
The (amide) C=O stretching band of finasteride slightly shifted to
a lower frequency (1668 cm−1), suggesting
intermolecular interaction between finasteride and β-cyclodextrin
in the inclusion complex (Fig. 6b) [17–19]. .
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