Phagocytic cell with highly partitioned perfluorodecalin droplets. Some perfluorocarbon-based blood substitutes show this phenotype, i.e. that of being segregated into individual small spherical droplets while others remain as large emulsion particles within phagocytes. A characteristic of the preferable blood substitutes (those which leave the body in a short half life, like emulsions of perfluorodecalin blood substitutes) is the ability for the emulsion particles to become smaller and smaller single inclusions while many of those perfluorochemical emulsions which remain in the body are resistant to being "re-emulsified", so to speak, within the cells which phagocytose the emulsion particles initially. This seems to be a process which occurs regardless of species or cell type. Perfluorodecalin droplets (blue) and the dense "cap" which is presumably lysosomal in nature (and appears typically in instances where the perfluorochemical particles are re-emulsified by the phagocyte; blue-green). Background cytoplasm, amber. Tissue fixed for routine electron microscopy, magnification of the microscope is 23000x.

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