= user generated What's this?
This image provided by:
Overview of expression changes (intervention spread vs. control spread) of 706 probesets (P < 0.01 for BMI × treatment effect) in nine lean (L left side) and eight overweight (O right side) subjects
When plotting the expression changes (intervention spread versus
control spread) of this set of 706 genes in the lean and overweight
subjects (Fig. 2 ), it can be seen that the expression
changes are more pronounced (larger fold changes) in the lean
subjects than in the overweight subjects.
Erk, Marjan J.; Pasman, Wilrike J.; Wortelboer, Heleen M.; Ommen, Ben; Hendriks, Henk F. J.Journal: Genes & Nutrition
Issue 3DOI: 10.1007/s12263-008-0096-zPublished: 2008-12-02Institution(s):
TNO Quality of Life
The goal of this study was to investigate the effect of a short-term nutritional intervention on gene expression in adipose tissue from lean and overweight subjects. Gene expression profiles were measured after consumption of an intervention spread (increased levels of polyunsaturated fatty acids, conjugated linoleic acid and medium chain triglycerides) and a control spread (40 g of fat daily) for 9 days. Adipose tissue gene expression profiles of lean and overweight subjects were distinctly different, mainly with respect to defense response and metabolism. The intervention resulted in lower expression of genes related to energy metabolism in lean subjects, whereas expression of inflammatory genes was down-regulated and expression of lipid metabolism genes was up-regulated in the majority of overweight subjects. Individual responses in overweight subjects were variable and these correlated better to waist–hip ratio and fat percentage than BMI.
This image is from the article titled "Short-term fatty acid intervention elicits differential gene expression responses in adipose tissue from lean and overweight men"
(from Genes & Nutrition), which is copyrighted by The Author(s). For more information on the
copyright for this image, please refer to the full image caption and to the
This image is published with open access and made available for noncommercial purposes. For more information on what you are allowed to do with this image, please see the Creative Commons pages.
To request permissions to use any copyrighted material, please visit the source document.
Report a copyright concern regarding this image.
Log in or register to save your favorite images and download them as high-quality PowerPoint or PDF files.
Log in or register to save your search criteria.
© Springer, part of Springer Science+Business Media.
Remote Address: 184.108.40.206 Server: 19